Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity

Meiho University Institutional Repository > 健康暨護理學院 > 食品營養系 > 期刊論文 > Item 987654321/4175

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.meiho.edu.tw/ir/handle/987654321/4175

题名:	Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity
作者:	Cao, Yi-ni Yue, Shan-shan Wang, An-yi Xu, Lu Hu, Yi-tong Qiao, Xue Wu, Tung-Ying Ye, Min Wu, Yang-Chang Qi, Rong
贡献者:	健康暨護理學院
关键词:	Nonalcoholic fatty liver disease Antrodia cinnamomea Dehydroeburicoic acid Aldehyde dehydrogenase 2 4-HNE
日期:	2022
上传时间:	2023-12-28T06:53:22Z (UTC)
摘要:	Ethnopharmacological relevance: Nonalcoholic fatty liver disease (NAFLD) is a prevalent liver disease, but currently has no specific medication in clinic. Antrodia cinnamomea (AC) is a medicinal fungus and it has been shown that AC can inhibit high fat diet (HFD)-induced lipid deposition in mouse livers, but the effective monomer in AC and mechanism against NAFLD remain unclear. It has been reported that aldehyde dehydrogenase 2 (ALDH2) activation shows protective effects on NAFLD. Our previous study demonstrates that AC and its monomer dehydroeburicoic acid (DEA) can upregulate the ALDH2 activity on alcoholic fatty liver disease mouse model, but it is not clear whether the anti-NAFLD effects of AC and DEA are mediated by ALDH2. Aim to study: To elucidate the active compound in AC against NAFLD, study whether ALDH2
显示于类别:	[食品營養系] 期刊論文

文件中的档案:

档案	描述	大小	格式	浏览次数
4. Journal of Ethnopharmacology 292 (2022)_參考作 (2).pdf		17022Kb	Adobe PDF	269	检视/开启

检视Licence

在MUIR中所有的数据项都受到原著作权保护.