A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados

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Title:	A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados
Authors:	Tsai, Tsung-Chang;Wu, Yu-Jen;Su, Jui-Hsin;Lin, Wei-Tung;Lin, Yun-Sheng
Contributors:	健康暨護理學院
Keywords:	spatane diterpenoid;soft coral;Sinularia leptoclados
Date:	2013
Issue Date:	2013-11-08T07:35:10Z (UTC)
Abstract:	A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562.
Relation:	Marine Drugs
Appears in Collections:	[Department of Biological Science and Technology] Papers

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