Anti-inflammatory cembranoids from the Formosan soft coral Sinularia discrepans.

Meiho University Institutional Repository > 健康暨護理學院 > 護理系 > 期刊論文 > Item 987654321/1805

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.meiho.edu.tw/ir/handle/987654321/1805

题名:	Anti-inflammatory cembranoids from the Formosan soft coral Sinularia discrepans.
作者:	Lu Y;Su HJ;Chen YH;Wen ZH;Sheu JH;Su JH
日期:	2011-09
上传时间:	2012-09-24T07:19:15Z (UTC)
摘要:	A new cembranoid, discrepanolide A (1), along with four known cembranoids 2-5 were isolated from the Formosan soft coral Sinularia discrepans. The structures of these compounds were determined by analysis of spectroscopic data and by comparison of NMR data with those of known compounds. None of these compounds were found to be cytotoxic towards a limited panel of cancer cell lines. Compounds 3-5 were found to display significant in vitro anti-inflammatory activity in LPS-stimulated RAW264.7 macrophage cells by inhibiting the expression of the iNOS protein. Compound 5 also significantly inhibited the accumulation of pro-inflammatory COX-2 protein.
關聯:	Arch Pharm Res. 2011 Aug;34(8):1263-7. Epub 2011 Sep 11.
显示于类别:	[護理系] 期刊論文

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html	full text	0Kb	HTML	1840	检视/开启
Archives of Pharmacal Research 2011 1263.pdf	full text	1245Kb	Adobe PDF	0	检视/开启

检视Licence

在MUIR中所有的数据项都受到原著作权保护.