Meiho University Institutional Repository:Item 987654321/401
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    MUIR > Journal of Meiho University > n.15(1997/06) >  Item 987654321/401


    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/401


    Title: 光療法對正常及唐氏症新生兒淋巴球中姊妹染色分體交換頻率之影響
    Authors: 吳芳鴦
    王瑞筠
    Contributors: 美和護理管理專科學校醫務管理科副教授‧中國醫藥學院環境醫學研究所兼任副教授
    中國醫藥學院公共衛生系講師
    Keywords: 藍色燈;綠色燈;唐氏症兒;姊妹染色分體交換;DNA損傷
    Date: 1997-06
    Issue Date: 2011-03-11T02:15:14Z (UTC)
    Abstract: 施行光療法時,經常使用藍色燈或綠色燈做為治療新生兒黃疸。為了檢查藍色燈及綠色燈兩種光源對染色體DNA之影響,故以唐氏症及核型正常的新生兒之末梢淋巴球為研究對象,在G0期的淋巴球細胞被暴露於籃色燈或綠色燈,再以傳統方式培養細胞。
    我們發現藍色燈照射後,其SCE頻率不論是唐氏症兒或正常兒均有顯著性的增加,但綠色燈照射後比藍色燈所誘發的SCE頻率較少。由研究資料顯示藉由藍色燈照射可能會引起DNA損傷,且唐氏症兒的細胞比之於正常兒的細胞較敏感。因此,在位唐氏症兒施行光療法時,需特別謹慎的處理。
    Appears in Collections:[Journal of Meiho University] n.15(1997/06)

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