Meiho University Institutional Repository:Item 987654321/2925
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    MUIR > Seminar >   >  Item 987654321/2925


    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/2925


    Title: 荖葉萃取物Chavibetol 抑制黑色素合成機制之研究
    Authors: 侯羿任;吳裕仁
    Keywords: 荖葉;黑色素細胞;酪胺酸酶活性
    Date: 2015
    Issue Date: 2015-11-22T04:07:40Z (UTC)
    Abstract: 據報導指出將荖葉蒸熟後敷臉可以達到美白之效果,所以本研究將利用荖葉萃取 物加入小鼠黑色素瘤細胞株B16 來看是否具有抑制黑色素合成之功效,首先添 加不同劑量之萃取物與小鼠黑色素瘤細胞株做MTT 實驗,在細胞沒有被毒殺的 情況下,再進行荖葉萃取物與小鼠黑色素瘤細胞株酪胺酸酶活性測試,發現荖葉 萃取物能有效抑制酪胺酸酶活性,降低黑色素合成量,可以初步的證實荖葉萃取 物有美白的效果,所以本實驗再利用蛋白質體學的技術,進行小鼠黑色素瘤細胞 株與荖葉萃取物之電泳分析,驗證是否有走向抑制酪胺酸脢,減少黑色素合成量 之途徑,達到美白之效果,未來將設計含有荖葉萃取物之保養品配方,進行安全 性與有效性之評估,進而開發含有荖葉萃取物之美白保養品。
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