A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives

MUIR > Graduate Institute of Health Care > Department of Nursing > Papers > Item 987654321/1802

Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/1802

Title:	A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives
Authors:	En-Chiuan Chang;Ya-Lan Wen;Chun-Hsi Chang;Yun-Hwei Shen;Shaw-Bing Wen;Mou-Yung Yeh;Fung Fuh Wong
Keywords:	2-Arylpyrazolo[3,4-c]quinolin-4(5H)-ones;2-Arylpyrazolo[4,3-c]quinolin-4(5H)-ones;3-Aryl sydnone;1,3-Dipolar cycloaddition;Suzuki coupling reaction;Adenosine receptor
Date:	2012-07
Issue Date:	2012-09-24T06:41:58Z (UTC)
Abstract:	Two regioisomers of 2-arylpyrazolo[3,4-c]quinolin-4(5H)-ones and 2-arylpyrazolo[4,3-c]quinolin-4(5H)-ones were synthesized by utilizing 3-arylsydnones, ethyl 3-bromopropynoate, and 2-aminophenylboronic acid pinacol ester in presence of catalytic agent Pd(PPh3)4. This efficient one-pot synthesis methodology involved 1,3-dipolar cycloaddition, Suzuki coupling reaction, and intramolecular cyclization three sequence steps.
Relation:	Tetrahedron Volume 68, Issue 29, 22 July 2012, Pages 5920–5924
Appears in Collections:	[Department of Nursing] Papers

Files in This Item:

File	Description	Size	Format
index.html	full text	0Kb	HTML	1006	View/Open
paper2.pdf	full text	250Kb	Adobe PDF	1	View/Open

View Licence