Meiho University Institutional Repository:Item 987654321/1098
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    题名: Salbutamol residues in swine tissues and body fluids after feeding
    作者: Ming Jen Hung;Han Hsiang Huang;Chao Ling Chen;Yu Jen Wu;Katie Marie Dixon;Chi Liang Mao
    贡献者: Department of Veterinary Medicine, National Chung-Hsing University, Taiwan;Department of Biological Science and Technology, Meiho University, Taiwan;Department of Veterinary Medicine, National Chung-Hsing University, Taiwan;Department of Beauty Science, Meiho University, Taiwan;Discipline of Pathology, Faculty of Medicine, University of Sydney, Australia;Department of Veterinary Medicine, National Chung-Hsing University, Taiwan
    关键词: salbutamol;residues;tissues;distribution;urine
    日期: 2010-12
    上传时间: 2011-09-14T08:20:56Z (UTC)
    摘要: Salbutamol residues in swine tissues and fluids were investigated. Tissue, serum and urine samples were collected from 33 pigs following 14-day oral administration of 3ppm salbutamol. The concentrations of salbutamol were determined by enzyme-linked immunosorbent assay and further confirmed by capillary electrophoresis. The highest urinary concentration of salbutamol was 145.12 ng/mL at 18 hour and remained detectable 30 days following last feeding. Salbutamol was undetectable in serum samples. The highest concentrations of salbutamol in liver, kidney, lung, heart, brain and muscle were 70.42 ng/mL, 31.88 ng/mL, 26.06 ng/mL, 6.76 ng/mL, 3.41 ng/mL and 2.97 ng/mL, respectively. Stomach and large intestine retained salbutamol residue for 11 days which is longer than those in the liver, lung, brain (4 days) and other tissues (2 days). The data shown in this study will be helpful for the screening of salbutamol residues and regulations on its illegal use in pigs.
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